Detalles de la búsqueda
1.
Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with Covid-19.
N Engl J Med;
390(13): 1186-1195, 2024 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38598573
2.
Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study.
Hepatology;
78(1): 258-271, 2023 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36994719
3.
Diagnostic accuracy of non-invasive tests to screen for at-risk MASH-An individual participant data meta-analysis.
Liver Int;
2024 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38573034
4.
NAFLD and NASH biomarker qualification in the LITMUS consortium - Lessons learned.
J Hepatol;
78(4): 852-865, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36526000
5.
Lipid-Reduction Variability and Antidrug-Antibody Formation with Bococizumab.
N Engl J Med;
376(16): 1517-1526, 2017 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28304227
6.
Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients.
N Engl J Med;
376(16): 1527-1539, 2017 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28304242
7.
Evaluating bococizumab, a monoclonal antibody to PCSK9, on lipid levels and clinical events in broad patient groups with and without prior cardiovascular events: Rationale and design of the Studies of PCSK9 Inhibition and the Reduction of vascular Events (SPIRE) Lipid Lowering and SPIRE Cardiovascular Outcomes Trials.
Am Heart J;
178: 135-44, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27502861
8.
Effects of varenicline on smoking cessation in adults with stably treated current or past major depression: a randomized trial.
Ann Intern Med;
159(6): 390-400, 2013 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24042367
9.
Cardiovascular safety of varenicline: patient-level meta-analysis of randomized, blinded, placebo-controlled trials.
Am J Ther;
20(3): 235-46, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23615317
10.
Proactive multifactorial intervention strategy reduces the risk of cardiovascular disease estimated with region-specific risk assessment models in Pacific Asian patients participating in the CRUCIAL trial.
J Korean Med Sci;
28(12): 1741-8, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24339703
11.
Anti-drug Antibody Magnitude and Clinical Relevance Using Signal to Noise (S/N): Bococizumab Case Study.
AAPS J;
25(5): 85, 2023 09 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37658997
12.
Population PK/PD modeling of low-density lipoprotein cholesterol response in hypercholesterolemic participants following administration of bococizumab, a potent anti-PCSK9 monoclonal antibody.
CPT Pharmacometrics Syst Pharmacol;
12(12): 2013-2026, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37994400
13.
Biomarkers for staging fibrosis and non-alcoholic steatohepatitis in non-alcoholic fatty liver disease (the LITMUS project): a comparative diagnostic accuracy study.
Lancet Gastroenterol Hepatol;
8(8): 714-725, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36958367
14.
Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & validation of imaging modality performance across the NAFLD spectrum in a prospectively recruited cohort study (the LITMUS imaging study): Study protocol.
Contemp Clin Trials;
134: 107352, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37802221
15.
The Fagerström Test for Nicotine Dependence as a predictor of smoking abstinence: a pooled analysis of varenicline clinical trial data.
Nicotine Tob Res;
14(12): 1467-73, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22467778
16.
Efficacy and safety of an orally administered DGAT2 inhibitor alone or coadministered with a liver-targeted ACC inhibitor in adults with non-alcoholic steatohepatitis (NASH): rationale and design of the phase II, dose-ranging, dose-finding, randomised, placebo-controlled MIRNA (Metabolic Interventions to Resolve NASH with fibrosis) study.
BMJ Open;
12(3): e056159, 2022 03 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35354614
17.
Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering?
Eur Heart J;
31(21): 2650-9, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20494902
18.
The use of a single-pill calcium channel blocker/statin combination in the management of hypertension and dyslipidemia: a randomized, placebo-controlled, multicenter study.
J Clin Hypertens (Greenwich);
11(1): 22-30, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19125855
19.
Assessing the Potential Risk of Cross-Reactivity Between Anti-Bococizumab Antibodies and Other Anti-PCSK9 Monoclonal Antibodies.
BioDrugs;
33(5): 571-579, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31529318
20.
First in human phase I trial of 852A, a novel systemic toll-like receptor 7 agonist, to activate innate immune responses in patients with advanced cancer.
Clin Cancer Res;
13(23): 7119-25, 2007 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18056192